Human beings around the globe have been suffering from a devastating novel pandemic and public health emergency, coronavirus disease 2019 (COVID-19), for more than one and a half years due to the deadly and highly pathogenic severe acute respiratory coronavirus 2 (SARS-CoV-2) infection worldwide.Notably, no effective treatment strategy has been app
This is a case report of a 29 year old male with pneumocystis pneumonia and tuberculosis, and who was initially suspected of having HIV infection, based on risk factor analyses, but was subsequently shown to be HIV negative.The patient arrived at the hospital with fever, cough, weight loss, loss of appetite, pallor, and arthralgia.In addition, he w
Chuyen Thi Hong Nguyen, Nguyet Huu Minh Nguyen, Trung The Van Department of Dermatology, University of Medicine and Pharmacy at Ho Chi Minh City, 700000, VietnamCorrespondence: Chuyen Thi Hong Nguyen, Department of Dermatology, University of Medicine and Pharmacy at Ho Chi Minh City, 217 Hong Bang Street, Ward 11, District 5, Ho Chi Minh City, Viet
Regulation of gene expression through histone modifications Bushings underlies cell homeostasis and differentiation.Kdm4d and Kdm4dl exhibit a high degree of similarity and demethylate H3K9me3.However, the physiological functions of these proteins remain unclear.In this study, we generated Kdm4dl mutant mice and found that Kdm4dl was dispensable fo